Which vasopressor is commonly used in the management of septic shock?

Norepinephrine is the vasopressor of choice in the management of septic shock because it effectively increases vascular tone and systemic vascular resistance, which helps improve blood pressure in patients experiencing this life-threatening condition. Septic shock is characterized by severe hypotension due to systemic vasodilation caused by sepsis, and norepinephrine works primarily on alpha-1 adrenergic receptors to induce vasoconstriction, thereby enhancing perfusion to vital organs.

Additionally, norepinephrine also has some beta-1 adrenergic activity, which can support cardiac output without causing significant increases in heart rate, making it particularly beneficial in the context of septic shock where maintaining organ perfusion is critical. The use of norepinephrine is recommended as a first-line treatment based on clinical guidelines, emphasizing its role in restoring hemodynamic stability in septic patients.