Which of the following is a common symptom of Cushing's syndrome?

In Cushing's syndrome, the body is exposed to high levels of cortisol for an extended period, which leads to various physical and metabolic symptoms. One of the common effects of elevated cortisol levels is hormonal imbalance that can disrupt the normal menstrual cycle, leading to irregular menstruation. This occurs because cortisol can inhibit the secretion of gonadotropin-releasing hormone (GnRH), affecting the hormones responsible for regulating the menstrual cycle.

Irregular menstruation is just one of several symptoms associated with Cushing's syndrome, which may also include weight gain, particularly around the abdomen and face, high blood pressure, and changes in mood. The other symptoms listed, such as insomnia, hypoglycemia, and excessive sleepiness, do not align with the typical manifestations of Cushing's syndrome. For instance, while insomnia might occur in some patients, it is not as definitive a symptom of the condition compared to menstrual irregularities. Additionally, individuals with Cushing's syndrome often experience hyperglycemia rather than hypoglycemia due to the effects of excess cortisol on glucose metabolism.