Which condition is characterized by centripetal obesity and thin skin?

Cushing's syndrome is characterized by centripetal obesity and thin skin due to excess cortisol production. This condition leads to the redistribution of body fat, particularly an accumulation in the trunk and face, while the limbs may appear thinner. The excess cortisol also causes changes in the skin, making it thinner and more fragile, leading to easy bruising and poor wound healing.

This hormonal imbalance can arise from various sources, including pituitary adenomas (Cushing's disease), adrenal tumors, or ectopic ACTH production, all of which result in high corticosteroid levels in the body. In contrast, the other conditions mentioned do not present with these specific symptoms. For instance, diabetes mellitus primarily leads to issues with blood sugar regulation and does not typically involve the specific fat redistribution or skin thinning seen in Cushing's syndrome. Dysbetalipoproteinemia involves lipid metabolism abnormalities and does not present with the features of centripetal obesity. Diabetes insipidus is related to an inability to concentrate urine due to a deficiency of antidiuretic hormone, manifesting with symptoms like excessive thirst and urination but not with changes in body fat distribution or skin texture.