What secondary condition can cause lymphadenopathy related to tumors?

Lymphadenopathy, which refers to the abnormal enlargement of lymph nodes, can be associated with various secondary conditions related to tumors. Neuroblastoma is a type of cancer that commonly affects children and originates from the neural crest tissue. As the tumor grows, it can lead to the activation of the immune response, resulting in lymphadenopathy due to the infiltration of cancer cells or the immune cells reacting to the presence of the tumor.

In the case of neuroblastoma, lymphadenopathy often occurs as a direct consequence of the disease progression. The cancer can metastasize to nearby lymph nodes or trigger them to enlarge as part of the body’s response to the malignancy. This is specifically linked to the neoplastic activity of the tumor, setting it apart from conditions like viral infections, autoimmune diseases, and Kawasaki disease, which can also cause lymphadenopathy but through different mechanisms that do not directly involve tumor pathology.

Therefore, neuroblastoma is the most relevant choice to directly link to tumor-related lymphadenopathy.