What is a common symptom of lipodystrophy?

Lipodystrophy is characterized by abnormal distribution of body fat, which can manifest as weight gain in specific areas of the body. This condition often leads to an accumulation of fat in certain regions, such as the abdomen, while causing loss of fat in others, such as the extremities. This specific pattern of fat gain aligns with the definition of lipodystrophy, making it a prominent and recognizable symptom.

The other options do not accurately reflect the manifestations of lipodystrophy. For instance, increased muscle mass is not a direct symptom of lipodystrophy; rather, it pertains to muscle growth which is not typically associated with fat distribution disorders. Uniform body fat distribution contradicts the very nature of lipodystrophy, where fat distribution is uneven. Finally, diabetes insipidus is a metabolic condition that affects water balance in the body and is not related to fat distribution or lipodystrophy itself. Therefore, weight gain in specific areas effectively summarizes a key symptom of this condition.